Benchmark Almanac

ReproBAIT

GPT-5.6 Sol 85% leads since Jun 2026 Only in system cards

Agents independently reproduce biological AI models from published scientific papers. Scored as success rate.

Third-party SecureBio evaluation reported in OpenAI system cards.

Made by SecureBio Genomics and life sciences Last in a system card Sep 2026 Last model added Sep 2026
Level
Expert Specialists with years of training, often over hours of work
Scored
Checked automatically A program checks the result against an answer key, unit tests or the expected final state.
Answers
Agent task Many steps in a terminal, browser, desktop, app, game or robot.
2
Models scored in lab cards
3
System cards report it, from 1 lab

GPT-5.6 Sol leads with 85%

Best score per model as labs report them in their own cards. Labs pick their own settings, so these compare less cleanly than independent runs.

  1. 1 GPT-5.6 Sol 85%
  2. 2 GPT-6 Astra 83%
#ModelScoreSettingDateSource
1 GPT-5.6 Sol 85% Jun 2026 Model card
2 GPT-6 Astra 83% Sep 2026 Model card

Number one over time

Lab claims count from the day the card came out, independent runs from the model’s release.

OpenAI
Lab claims Passed 85% in Jun 2026, by GPT-5.6 Sol

The best score passed 85% in Jun 2026

All the scores we have, one dot each, so a model tested at several settings appears more than once.

Reported by the lab in its model card
0% 20% 40% 60% 80% 100% 2026 Near the ceiling (85%) GPT-5.6 Sol 0% 20% 40% 60% 80% 100% 2026 Near the ceiling (85%) GPT-5.6 Sol

Labs report it only in system cards

We read the headline results of 479 launch posts from 51 labs, and none of them list this benchmark. Some system cards do, below.

3 system cards report it, from 1 lab

Besides launch posts, we read the system cards, model cards and technical reports labs publish with a release. They report far more, including safety and frontier-risk tests.

DateDocumentScoreAs the document writes itSection
3 Sep 2026 GPT-6 Astra system card 83 SecureBio ReproBAIT, share of published performance reached, helpful-only checkpoint, six tasks (10.1.1.4) Bio and chem risk
9 Jul 2026 GPT-5.6 Sol system card 85 SecureBio ReproBAIT, railfree variant of GPT-5.6 (9.1.1.8) Bio and chem risk
25 Jun 2026 GPT-5.6 Sol system card 85 SecureBio ReproBAIT, railfree variant of GPT-5.6 (9.1.1.8) Bio and chem risk

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