Catastrophic biology scenario uplift trial (Anthropic)
Only in system cards
PhD biologists with model access spend up to 16 hours planning a catastrophic biological scenario. External experts grade uplift and executability.
Human uplift trial. Anthropic reports whether any plan was judged both highly uplifted and credibly executable.
Made by Anthropic Hazardous knowledge Tasks kept private Last in a system card Apr 2026
Last model added Apr 2026
- Level
- Expert Specialists with years of training, often over hours of work
- Scored
- Graded by people Human experts grade or compare the outputs.
- Answers
- Open-ended Free-form text, documents, designs or media judged as a whole.
1
System card reports it, from 1 lab
No scores here yet
No lab, leaderboard or Epoch AI run has reported a score for Catastrophic biology scenario uplift trial (Anthropic) yet.
Labs report it only in system cards
We read the headline results of 479 launch posts from 51 labs, and none of them list this benchmark. Some system cards do, below.
One system card reports it
Besides launch posts, we read the system cards, model cards and technical reports labs publish with a release. They report far more, including safety and frontier-risk tests.
| Date | Document | Score | As the document writes it | Section |
|---|---|---|---|---|
| 7 Apr 2026 | Claude Mythos Preview system card | Catastrophic biology scenario uplift trial, 10 participants, no numeric score. No plan was judged both highly uplifted and likely to succeed (2.2.5.3) | Bio and chem risk |
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