Benchmark Almanac

Biotool and Wet Lab Actions

Only in system cards

Agents perform wet lab assistant tasks such as finding a genome file or ordering DNA through a computer or browser. Scored as pass@10 per task.

OpenAI Preparedness evaluation with three tasks and no overall score.

Made by OpenAI with Ranger Released Sep 2024 Hazardous knowledge Tasks kept private Last in a system card Jan 2025 Last model added Jan 2025
Level
Expert Specialists with years of training, often over hours of work
Scored
Checked automatically A program checks the result against an answer key, unit tests or the expected final state.
Answers
Agent task Many steps in a terminal, browser, desktop, app, game or robot.
5
System cards report it, from 1 lab

No scores here yet

No lab, leaderboard or Epoch AI run has reported a score for Biotool and Wet Lab Actions yet.

Labs report it only in system cards

We read the headline results of 479 launch posts from 51 labs, and none of them list this benchmark. Some system cards do, below.

5 system cards report it, from 1 lab

Besides launch posts, we read the system cards, model cards and technical reports labs publish with a release. They report far more, including safety and frontier-risk tests.

DateDocumentScoreAs the document writes itSection
31 Jan 2025 o3-mini system card Biotool and Wet Lab Actions, success rate over 10 rollouts on 3 tasks, no overall score (Table 11) Bio and chem risk
23 Jan 2025 OpenAI Computer-Using Agent (CUA) system card Biorisk tooling evaluation, pre-mitigation Operator model, 1% success on the task set, AlphaFold 2/10, Ebola FASTA 0/10, Twist DNA order 10/10 (Table 1, 3.3.1) Bio and chem risk
5 Dec 2024 o1 system card Biotool and Wet Lab Actions, pass@10 on 3 tasks (o1 post-mitigation 0% AlphaFold, 83% Ebola FASTA, 0% Twist DNA), no overall score (Table 13) Bio and chem risk
12 Sep 2024 o1-preview system card Biotool and Wet Lab Actions, pass@10 on 3 tasks (o1-preview post-mitigation 0% AlphaFold, 100% Ebola FASTA, 0% Twist DNA), no overall score (Table 8) Bio and chem risk
12 Sep 2024 o1-mini system card Biotool and Wet Lab Actions, pass@10 on 3 tasks (o1-mini post-mitigation 0% AlphaFold, 0% Ebola FASTA, 0% Twist DNA), no overall score (Table 8) Bio and chem risk

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