Organic Chemistry V2 (Anthropic)
Models predict structures from spectra, design multi-step syntheses, predict reaction products and read chemical structure images. V2 adds harder expert-recommended problems.
In-house Anthropic evaluation. Scores are not comparable with the original Organic Chemistry set.
- Level
- Expert Specialists with years of training, often over hours of work
- Scored
- Checked automatically A program checks the result against an answer key, unit tests or the expected final state.
- Answers
- Short answer A number, word or short string matched to a key.
Claude Opus 5 leads with 61.6%
Best score per model as labs report them in their own cards. Labs pick their own settings, so these compare less cleanly than independent runs.
- 1 Claude Opus 5 61.6%
| # | Model | Score | Setting | Date | Source |
|---|---|---|---|---|---|
| 1 | Claude Opus 5 | 61.6% | Jul 2026 | Model card |
Scores over time
All the scores we have, one dot each, so a model tested at several settings appears more than once.
Labs report it only in system cards
We read the headline results of 479 launch posts from 51 labs, and none of them list this benchmark. Some system cards do, below.
One system card reports it
Besides launch posts, we read the system cards, model cards and technical reports labs publish with a release. They report far more, including safety and frontier-risk tests.
| Date | Document | Score | As the document writes it | Section |
|---|---|---|---|---|
| 24 Jul 2026 | Claude Opus 5 system card | 61.6 | Organic chemistry, V2, 10 of 1,260 attempts timed out and were excluded (8.17.5) | Capabilities |
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